elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris

نویسندگان

firouz pouralibaba

department of oral medicine, faculty of dentistry zohreh babaloo

department of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran farzaneh pakdel

department of oral medicine, faculty of dentistry tahmoores abdollahian

department of oral medicine, faculty of dentistry solmaz pourzare

چکیده

background: pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes. objectives: to investigate the potential role of il-23 in pemphigus vulgaris. methods: in this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion and exclusion criteria. measurement of il-23 serum levels in blood samples was conducted by elisa. data was analyzed using student’s t-test for comparison of il-23 levels between the two groups. results: mean serum levels of il-23 in patients with pemphigus and healthy controls were 25.1 ± 4.2 and 17.9 ± 4.7 pg/ml, respectively (p

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منابع مشابه

Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris

Background: Pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes. Objectives: To investigate the potential role of IL-23 in pemphigus vulgaris. Methods: In this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion and...

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Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris.

BACKGROUND Pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes. OBJECTIVES To investigate the potential role of IL-23 in pemphigus vulgaris. METHODS In this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion an...

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Serum Interleukin-23 Levels in Patients with Ulcerative Colitis

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Serum Levels of Interleukin 17 in Patients with Pemphigus and Healthy Subjects

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Overexpression of Interleukin-23 and Interleukin-17 in the Lesion of Pemphigus Vulgaris: A Preliminary Study

IL-23/IL-17 axis has been identified as major factor involved in the pathogenesis of several autoimmune diseases; yet its pathogenetic role in pemphigus vulgaris (PV) remains controversial. The aim of this research was to investigate the potential role of IL-23/IL-17 axis in the immunopathogenesis of PV, and correlation between IL-23+ cells and IL-17+ cells was also evaluated. For this purpose,...

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عنوان ژورنال:
iranian journal of immunology

جلد ۹، شماره ۴، صفحات ۲۶۱-۲۶۵

کلمات کلیدی
[ ' a u t o i m m u n e d i s e a s e ' , ' i n t e r l e u k i n ' , 2 3 , ' p e m p h i g u s v u l g a r i s ' ]

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